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Endometrial Biopsy

Endometrial Biopsy Instructions

An endometrial biopsy is performed late in the menstrual cycle to help detect how well the uterine lining has developed since ovulation. This test is performed in the clinic and generally takes 2-3 minutes.

An endometrial biopsy is performed by placing a small straw-like instrument within the uterine cavity and removing a small amount of uterine lining. After the biopsy, patients should expect some vaginal spotting for the next 1-5 days. "Menstrual like" cramping the day of the exam and possibly the day after is sometimes experienced. We recommend that patients take their usual medication for menstrual cramps (Advil, ibuprofen, Motrin) and drink plenty of fluids.

Patients are advised to abstain from intercourse, refrain from using tampons or douching, and have no other vaginal entry for the next three days.

Symptoms to watch for include:

  1. Fever greater than 101°
  2. Increased cramping or pain
  3. Heavy bleeding for 1 hour
  4. Increase in bleeding
  5. Abnormal (foul or bad smelling) vaginal discharge

If you experience any of these symptoms or have questions, call us at 843-881-3900.



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Southeastern Fertility Center has offices in Charleston, Columbia, and Myrtle Beach, South Carolina.
We welcome patients from nearby areas including Beaufort, Savannah, Aiken, Florence, Greenville, Augusta, Georgia
and Wilmington North Carolina.

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Office Locations
1375 Hospital Drive, Charleston, South Carolina
1410 Blanding Street, Suite 204, Columbia, South Carolina
4728 Jenn Drive, Suite 102, Myrtle Beach, South Carolina